The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
qu fu qian lie su di yan ye zhi liao yuan fa xing kai jiao xing qing guang yan de lin chuang xiao guo guan cha
Author(s): 
Pages: 50-52
Year: Issue:  9
Journal: Chinese Journal of Postgraduates of Medicine

Keyword:  青光眼开角型眼内压曲伏前列素;
Abstract: 目的 观察曲伏前列素滴眼液治疗原发性开角型青光眼的疗效及安全性.方法 选取原发性开角型青光眼患者50例(66眼),按随机数字表法分为两组:观察组30例(42眼),给予曲伏前列素滴眼液,每晚1次,每次1滴;对照组20例(24眼),给予常规降眼压治疗.两组均治疗12周.观察治疗1,4,8,12周后的疗效、眼压及不良反应.结果 观察组治疗1,4,8,12周后眼压均明显低于对照组[(15.78±2.24) mmHg(1 mmHg=0.133 kPa)比(19.67±2.34) mmHg、(15.65±3.61) mmHg比(19.61 ±2.19) mmHg、(15.49±2.08) mmHg比(19.52±2.31) mmHg、(15.45±2.75) mmHg比(19.42±2.34) mmHg],差异有统计学意义(P<0.01).观察组治疗1,4,8,12周后总有效率均明显高于同期对照组[92.9%(39/42)比66.7% (16/24)、95.2%(40/42)比70.8%(17/24)、97.6%(41/42)比75.0%(18/24)、97.6%(41/42)比79.2%(19/24)],差异有统计学意义(P<0.05).观察组无一眼出现眼周皮下色素沉着,8眼出现结膜充血,3眼睫毛变长;对照组有5眼出现结膜充血.两组均未发现严重不良反应及全身性不良反应.结论 曲伏前列素滴眼液能安全有效地降低原发性开角型青光眼患者的眼压,而且不良反应小.
Related Articles
No related articles found