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Effect of Haitangping on Dyslipidaemia in Mouse Induced by Feeding High-Fat Diet
Author(s): 
Pages: 1317-1320
Year: Issue:  12
Journal: Transactions of Beijing Institute of Technology

Keyword:  HTPdisorder of lipid metabolismhigh fat diettriglyceridescholesterol;
Abstract: 研究射干茎叶提取物-海糖平(HTP)对高脂饲料诱导的小鼠脂代谢紊乱的改善作用.ICR小鼠连续12周高脂饲料喂养诱发脂质代谢紊乱.造模成功后分别灌胃给予海糖平50,100,200 mg/kg BW,治疗4周,并以吉非罗齐胶囊(100 mg/kg BW)作为阳性对照药.治疗结束后检测肝脏和血清中甘油三酯(TG)、总胆固醇(TC)含量,附睾脂肪组织重量等指标,同时做肝脏组织病理检查.结果显示海糖平能够降低肝脏中TG、TC水平及血清中TG水平,减轻附睾脂肪组织重量,减少肝细胞中脂滴的蓄积.证实海糖平具有改善高脂饲料喂养小鼠的血清和肝脏中脂质代谢紊乱的作用.
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