Author(s): ZHANG Kai-li, TIAN Li-jia, QIU Dan, YANG Lei, ZHANG Li-fang, College of Chemical Engineering, Ningbo University of Technology, College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Zhejiang NVB Co., Ltd.
Pages: 246-250
Year: 2014 Issue:  2
Journal: Science and Technology of Food Industry
Keyword:  vitamin E octenylsuccinate(VE-OS ester); 4-dimethylaminopyridine(DMAP); response surface methodology; conversion;
Abstract: Catalyzed by 4-dimethylaminopyridine(DMAP) and zinc powder(Zn),vitamin E octenylsuccinate(VE-OS ester) was synthesized by the reaction of octenylsuccinic anhydride(OSA) and vitamin E(VE). Each reaction factor of synthesis process was studied,and the synthesis of VE-OS ester was optimized by response surface methodology on the base of the single factor experiment,and a well-fitted mathematical model was established. Results showed that the amount of DMAP was the most significant factor for the reaction. The maximum theoretical VE conversion rate of 100% was obtained when the mole ratio of OSA to VE and DMAP to VE were 2.3 ∶1 and 0.2 ∶1,respectively,and the amount of solvent was 61.67mL. The real conversion rate was 99.04% according to the theoretical experimental condition(100%),indicating that the optimization of synthesis by response surface methodology was effective.