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The effect of Flurbiprofen ester effered preemptive analgesia in patients with vocal cord polyp removed by suspension Laryngoscope on serum levels of interleukin-6
Author(s): 
Pages: 51-52
Year: Issue:  6
Journal: Heilongjiang Medicine And Pharmacy

Keyword:  氟比洛芬酯超前镇痛声带息肉IL-6;
Abstract: 目的:观察氟比洛芬酯用于声带息内摘除术病人的超前镇痛及对Ⅱ-6的影响.方法:选择择期行声带息肉摘除术病人40例,随机分为两组,即氟比洛芬酯组(F组)和生理盐水组(N组).F组在诱导结束气管插管前静脉注射氟比洛芬酯1mg/kg,而N组静脉注射生理盐水.分别记录术后1、4、8和12h病人VAS和测定诱导前10min(T0)、术后1h(T1)、术后4h(T2)和术后12h(T3)血清IL-6的浓度.结果:F组术后各时点疼痛评分低于N组(P<0.05);与麻醉前相比,两组患者术后IL-6水平升高(P<0.05);与N组相比,F组在T1、L、T3时点血清IL-6水平较低(P<0.05).结论:氟比洛芬酯有良好的超前镇痛作用,且能够有效抑制术后IL-6的升高,在作用时间内发挥了一定的镇痛和抗炎作用,有利于病人身体的康复.
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