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jin zhan xing nao geng si huan zhe xian wei dan bai yuan he tong xing ban zuo an suan bian hua ji xiang guan xing yan jiu
Author(s): 
Pages: 1214-1215
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  进展性脑梗死纤维蛋白原同型半胱氨酸;
Abstract: 目的探讨进展性脑梗死患者纤维蛋白原(Fib)和同型半胱氨酸(Hcy)的变化及与其他相关指标的关系。方法将符合入选标准的246例急性脑梗死患者根据病情是否发展恶化将其分为进展性脑梗死组(61例)与非进展性脑梗死组(185例)。分析进展性脑梗死患者Fib、Hcy的变化及与其他相关指标的关系。结果入院后第2天、第7天,进展组患者Fib和Hcy均高于非进展组,差异有统计学意义(P<0.05);Pearsons相关性分析结果显示,Fib与全血黏度、全血还原黏度、血浆比黏度、红细胞比容呈显著正相关(r值分别为0.613、0.544、0.507、0.496,P<0.05);Hcy与颈动脉内中膜厚度(IMT)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)呈显著正相关(r值分别为0.593、0.601、0.527、0.452,P<0.05)。结论纤维蛋白原、同型半胱氨酸水平与进展型脑梗死密切相关。
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