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shui zuo ti qu wu dui guan xin bing bu wen ding xing xin jiao tong huan zhe xue guan nei pi gong neng de ying xiang
Pages: 1188-1189
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  冠心病不稳定型心绞痛水蛭提取物内皮功能;
Abstract: 目的观察水蛭提取物对冠心病不稳定型心绞痛(VAP)心血瘀阻证患者血清一氧化氮(NO)、内皮素-1(ET-1)、血栓素B2(TXB2)和6-酮-前列腺素(6-Keto-PGF1a)的影响。方法将60例冠心病不稳定型心绞痛心血瘀阻证患者随机分为水蛭提取物组(治疗组)和常规组(对照组)。治疗前和治疗后1个月分别测定血清NO、ET-1、TXB2和6-Keto-PGF1a水平。结果治疗组治疗后NO、6-Keto-PGF1a水平升高,ET-1、TXB2水平下降,与对照组治疗后比较差异有统计学意义(P<0.05)。结论水蛭提取物具有改善冠心病不稳定型心绞痛心血瘀阻证患者血管内皮功能的作用。
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