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The Efficacy and Safety of Rosuvastatin Calcium Tablets for Treatment of Hyperlipidemia
Author(s): 
Pages: 1161-1163
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  hyperlipidemiarosuvastatin calciumatrovastatin;
Abstract: Objective To observe the therapeutic effects and safety of rosuvastatin calcium on hyperlipidemia.Methods F ortyeight patients with hypercholesterolemia were screened out after 4-weeks of stopping of hypolipidemic treatment,during which patients received drug A(5mg of rosuvastatin calcium once daily,group A1;10mg of which,group A2) or drug B(10mg of atrovastatin once daily,group B)f or 8weeks.Results Compared with that bef ore treatment,the levels of low density lipoprotein cholesterol(LDL-C),total cholesterol(TC)and triglyceride(TG)among the three groups were decreased in 4and 8week after treatment,and the difference was statistically significiant(P<0.05).The level of LDL-C in group B was lower than that in group A1and group A2at eight weekend(P<0.05),and there was no significant differences among group A1and group A2(P>0.05).The success rate in group B was lower than that in group A1and group A2(P<0.05).Conclusion Rosuvastatin calcium with 5mg to 10mg once daily can reduce the levels of LDL-C and TC.It is an efficient and safe approach in the treatment of hyperlipidemia.
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