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Protective Effects of Suxiao Jiuxin Pill on Myocardium in Stable Angina Pectoris after PCI
Pages: 1156-1159
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  stable angina pectorisSuxiao Jiuxin pillpercutaneous coronary interventionmyocardial infarctioncoronary blood flow;
Abstract: Objective To investigate the protective effects of Suxiao Jiuxin pill(SJP)on myocardium f or the patients with stable angina(SA)underwent percutaneous c oronary intervention(PCI).Methods Sixty SA patients with blood stasis syndrome due to qi stagnation,underwent c oronary angiography and PCI,were randomly divided into two groups:Control group(n=30)treated with standard western medicine,treatment group(n=30)treated with SJP and standard western medicine.To investigate the effects of SJP,myocardial enzymes,c oronary blood flow,and the incidence of perioperative myocardial infarction were compared bef ore and after PCI.Results Bef ore PCI,26 cases in treatment group had 3 grades thrombolysis in myocardial infarction(TIMI)flow and 20 cases in control group(P>0.05).After PCI,30 cases in treatment group had 3 grades TIMI flow and 26 cases in control group(P=0.056).There was a trend of the c oronary blood flow in treatment group was better than that in control group after PCI.The myocardial enzymes were decreased in both groups.The concentration of TnI in 24 hours after PCI had significant difference(P<0.05)between two groups.Compared with the control group,the incidence of perioperative myocardial injury and myocardial infarction were significantly lower in treatment group(P<0.05).Conclusion Compared with standard western medicine,SJP plus standard western medicine therapy could further reduce the myocardial enzymes level,improve the c oronary blood flow,decrease the incidence of perioperative myocardial infarction in the SA patients bef ore and after PCI.
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