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xin ji que xue yu shi ying dui ji xing xin ji geng si lin chuang he jin qi yu hou jia zhi de tan tao
Author(s): 
Pages: 1184-1186
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  急性心肌梗死缺血预适应心肌损伤心律失常;
Abstract: 目的观察心肌缺血预适应对急性心肌梗死病人心肌损伤程度、恶性心律失常的发生和近期预后的影响。方法选择286例急性心肌梗死病人,分为缺血预适应组(IP组)158例,无缺血预适应组(NIP组)132例。均于入院后及入院24h内多次测定心肌肌酸激酶(CK)、肌酸磷酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)及肌钙蛋白I(cTnI),取其峰值;比较两组恶性心律失常及心血管事件的发生率。结果 IP组CK、CK-MB、LDH、cTnI峰值浓度显著低于NIP组(P<0.01)。IP组病人心功能不全、心衰、梗死后心绞痛、恶性心律失常的发生率明显低于NIP组(P<0.01)。结论缺血预适应可减少其后发生急性心肌梗死病人心肌损伤面积,减少恶性心律失常及近期心脏事件的发生。
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