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xiao ben di ping kong shi pian yu ben huang suan an lv di ping pian zhi liao yuan fa xing gao xue ya de lin chuang dui bi yan jiu
Author(s): 
Pages: 1267
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  原发性高血压硝苯地平控释片苯磺酸氨氯地平片;
Abstract: 目的比较硝苯地平控释片(拜新同)与苯磺酸氨氯地平片治疗原发性高血压的临床疗效及不良反应。方法将112例原发性高血压患者随机分为研究组和对照组,其中对照组采用拜新同治疗,研究组采用氨氯地平治疗,比较两种药物治疗的临床疗效及不良反应。结果两组治疗后收缩压及舒张压比较差异无统计学意义(P>0.05)。研究组临床降压疗效总有效率92.86%,对照组为85.71%,两组比较差异无统计学意义(χ2=1.49,P>0.05)。研究组的不良反应发生率(5.36%)明显低于对照组(17.86%),差异有统计学意义(χ2=4.26,P<0.05)。结论拜新同与苯磺酸氨氯地平片均能显著降压,但是苯碘酸氨氯地平片除具有较好的降压效果和依从性,其不良反应发生率较拜新同低。
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