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xp11.2 yi wei xiang guan xing shen xi bao ai de lin chuang te dian
Author(s): 
Pages: 79-83
Year: Issue:  7
Journal: Journal of Shandong University(Health Sciences)

Keyword:  肾肿瘤Xp11.2易位TFE3基因融合蛋白;
Abstract: 目的总结Xp11.2易位相关性肾细胞癌的临床特点,探讨Xp11.2易位相关性肾细胞癌的诊断治疗思路。方法收集山东大学齐鲁医院泌尿外科2011~2012年3例Xp11.2易位相关性肾细胞癌患者的临床及随访资料,对术后标本处理后进行分析总结,并结合文献资料复习。结果 3例患者中,2例因无痛性肉眼血尿检查发现,1例因健康查体发现。3例患者CT扫描结果示肾脏肿块平均4 cm×5 cm,肿块内均可见点状钙化,增强扫描后呈不均匀强化。免疫组织化学和RT-PCR均证实为Xp11.2易位相关性肾细胞癌。结论 Xp11.2易位相关性肾细胞癌的有效治疗方案仍在研究探索中。
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