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Detection and significance of CD4+CD25 high Treg in the peripheral blood of patients with newly diagnosed rheumatoid arthritis
Pages: 849-850,853,封3
Year: Issue:  8
Journal: Modern Practical Medicine

Keyword:  关节炎类风湿CD4+CD25+ Treg免疫耐受;
Abstract: 目的 探讨CD4+CD25high调节性T细胞(CD4+CD25high Treg)在类风湿性关节炎(RA)发病机制中的作用.方法 采用流式细胞仪(FCM)检测42例RA患者及23例健康对照组外周血CD4+CD25high Treg的数量.结果 RA患者组及对照组外周血CD4+CD25high Treg的表达为(2.69± 1.85)%和(3.83±0.89)%,RA患者组CD4+CD25highTeg的表达低于对照组,差异有统计学意义(P< 0.01).结论 RA组患者CD4+CD25high Treg表达下降.
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