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nogo-b de sheng wu xue gong neng
Author(s): 
Pages: 445-450
Year: Issue:  4
Journal: Acta Physiologica Sinica

Keyword:  Nogo-B组织修复炎症凋亡阿尔茨海默病;
Abstract: Nogo-B是网状蛋白家族4的重要成员,其广泛表达于中枢神经系统及外周组织,其亚细胞定位于细胞内质网及细胞膜。研究显示,Nogo-B主要参与血管损伤、组织修复、再生及炎症过程的调控,并可能在肿瘤细胞凋亡及中枢神经系统疾病中也发挥重要作用。对Nogo-B的结构及其功能的进一步探索,有助于更加深入地了解其在各种疾病中发挥作用的机制。
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