Response-guided therapy and withdrawal time of peginterferon α for HBeAg-negative chronic hepatitis B
Author(s): ZHU Yue-yong, JIANG Jia-ji
Pages: 488-490
Year: 2013 Issue: 7
Journal: Chinese Journal of Hepatology
Keyword: Hepatitis B; chronic; Hepatitis B e antigens; Peginterferon; Response guided therapy; Withdrawal;
Abstract: 我国HBeAg阴性慢性乙型肝炎(CHB)占CHB患者的30％ ～ 40％,且有增长趋势[1];以基因B、C型为主.HBeAg阴性CHB患者ALT持续或反复异常,肝组织学检查肝脏病变较重,病情缓解比例低,发生肝硬化、临床失代偿和肝细胞肝癌(HCC)概率高;对当前治疗的应答率低、复发率高.
Pages: 488-490
Year: 2013 Issue: 7
Journal: Chinese Journal of Hepatology
Keyword: Hepatitis B; chronic; Hepatitis B e antigens; Peginterferon; Response guided therapy; Withdrawal;
Abstract: 我国HBeAg阴性慢性乙型肝炎(CHB)占CHB患者的30％ ～ 40％,且有增长趋势[1];以基因B、C型为主.HBeAg阴性CHB患者ALT持续或反复异常,肝组织学检查肝脏病变较重,病情缓解比例低,发生肝硬化、临床失代偿和肝细胞肝癌(HCC)概率高;对当前治疗的应答率低、复发率高.
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