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Apoptosis during placentation
Author(s): 
Pages: 409-413
Year: Issue:  6
Journal: ACTA PHYSIOLOGICA SINICA

Keyword:  凋亡胎盘发生免疫耐受Fas/FasL;
Abstract: 细胞凋亡是一种正常的生理现象.在胚泡着床过程中, 伴随有大量细胞凋亡.研究表明, 胎盘发生过程中的细胞凋亡, 对调控子宫内膜基质细胞的蜕膜化和滋养层细胞的浸润以形成胎盘具有重要意义; 另外, 由Fas/FasL系统介导的细胞凋亡可能与母体对胎儿的免疫耐受性有关.本文主要评述细胞凋亡的一般通路以及胎盘发生过程中细胞凋亡的调控.
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