Author(s): Alireza Rafiei, Jeremy J Gilbreath, D Scott Merrell, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari 48471-91971, Iran, Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States
Pages: 3711-3712
Year: 2013 Issue:  23
Journal: World Journal of Gastroenterology
Keyword:  Inducible nitric oxide synthetase; Helicobacter pylori; Gastric cancer;
Abstract: In a recent study, Rafiei et al, reported a link between a C150T polymorphism in the human inducible nitric oxide gene and Helicobacter pylori infection as a risk factor for gastric cancer among an Iranian population. Subsequently, Abadi and Kusters published a letter to the editor questioning the validity of the study because of a supposed flaw in primer design. Here we respond to the claims of Abadi and Kusters and show that the results reported in the original article are valid.