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th22 xi bao yu zhi qi guan xiao chuan
Author(s): 
Pages: 350-353
Year: Issue:  4
Journal: Chinese Bulletin of Life Sciences

Keyword:  Th22细胞IL-22支气管哮喘;
Abstract: 支气管哮喘是一种临床上常见的呼吸道疾病,研究发现CD4+T细胞在哮喘的发病过程中起重要作用。Th22细胞是最近发现的一类CD4+T细胞功能亚群之一,其主要效应因子IL-22在炎症性疾病、组织修复、创口愈合及自身免疫性疾病中起重要作用,但其具体机制尚未完全清楚。从Th22的细胞因子来源、生物学特性、分化和调控出发,简要探讨Th22细胞与哮喘之间的可能关系。
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