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xin hao fen zi ppgpp yu wei sheng wu huan jing shi ying xing
Pages: 385-389
Year: Issue:  4
Journal: Chinese Bulletin of Life Sciences

Keyword:  ppGppstringent responseenvironmental adaptation;
Abstract: 微生物能感知环境胁迫信号,通过触发严谨反应对生长速率进行调节,并通过一系列代谢调控,使细胞能在不利环境中生存。高度磷酸化的鸟苷四/五磷酸ppGpp/pppGpp(文中以ppGpp统称)作为信号分子对微生物生理具有广泛的调节作用,至今仍是微生物学研究热点之一。ppGpp对于微生物适应高温、高压等环境起到了积极的作用。综述了信号分子ppGpp合成降解机制及其调控微生物适应性方面的研究进展。
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