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zuo jia mi dui shi yan tu gong xing chong bing de liao xiao guan cha
Author(s): 
Pages: 22-26
Year: Issue:  2
Journal: Acta Parasitology et Medica Entomologica Sinica

Keyword:  Artemether Toxoplasma gondii Circulating antigen;
Abstract: Rabbits were infected with T.gondii tachyzoites of the RH strain via abdominal cavity. The evalution on the effects of Art included survival rates of the rabbit and dynamic changes of CAg in rabbit sera. The results indicated that CAg could be detected on the first day after infection. In the group without any treatment, the CAg began to rise on day 4 and reach its peak level on day 7 after infection and then dropped rapidly. Some of the rabbits sera turned negative on day 30. But in the group with treatment, the CAg was rapidly increased and reached its peak level on day 4 and then began to drop. All of the CAg was converted negative from day 7 to day 23 post-infection. In addition, All Art administrated rabbits were protected from death. It demonstrates that the detection of CAg is helpful for evaluating the effect of treatment and Art could be effective for curing toxoplasmosis.
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