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fan liu xing shi guan yan
Author(s): 
Pages: 407-409+396
Year: Issue:  9
Journal: International Journal of Internal Medicine

Keyword:  下端食管括约肌压力反流性食管炎鳞状柱状粘膜交界处;
Abstract: 反流性食管炎(RE)的治疗旨在加强抗反流屏障,增强食管清除能力,改善胃排空及括约肌功能,减少胃内容数量与酸度,以保护受损组织。西沙必利(cisapride)是唯一已证实有效的促动力药物。常规剂量 H2受体阻断药或硫糖铝单一使用可达到相同的症状缓解与病变愈合的效果。H2受体阻断药晚餐后给药能有效地抑制夜间泌酸,用更大剂量 H2受体阻断药或奥美拉唑(omeperazole)则症状缓解与愈合会更快。是否必要维持低酸或无酸状态尚待明确。
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