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Author:
Journal / Book Title:
Year:
Volume:
Issue:
nei pi su
Author(s):
CHABRIER Pe
,
WANG Zhenyi
Pages:
173
-
174
Year:
1992
Issue:
4
Journal:
International Journal of Internal Medicine
Keyword:
EC
;
endotheliocyte 内皮细胞
;
ET
;
endotheline 内皮素
;
Abstract:
<正> 人体血管表面总面积约有1000M
2
,覆盖着一层血管内皮细胞(EC)。EC 除能合成诸如前列环素、内皮源松弛因子(EDRF)等使血管松弛、抗血小板聚集的物质外,还能分泌一种缩血管肽,名为内皮素(ET)。1988年由 Yanagisawa及 Masaki 等人发现和提纯。结构与生物合成ET 是从猪 EC 培养上清液中分离和提纯的,含21个氮基酸(NH
2
-半胱·丝·半胱·丝·丝·亮·蛋·天冬·赖·甘·半胱·缬·酪·丙·半胱·组·亮·天冬·异亮·异亮·色
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