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The changes and its clinical value of serum homocysteine and lipoprotein(a) in patients with subclinical hypothyroidism before and after levothyroixine repacement treatment
Author(s): 
Pages: 432-434
Year: Issue:  4
Journal: Anhui Medical Journal

Keyword:  甲状腺功能减退症亚临床同型半胱氨酸脂蛋白(a);
Abstract: 目的 观察亚临床甲状腺功能减退症(亚临床甲减)患者经甲状腺激素治疗前后血清同型半胱氨酸(Hcy)及脂蛋白(a)[Lp(a)]的浓度变化,寻找亚临床甲减与其之间的关系.方法 选择2009年1月至2012年9月来院就诊的亚临床甲减患者36例(其中门诊患者25例,住院患者11例),分别在初诊和左旋甲状腺激素治疗8~l2周后观察甲状腺功能(FT3、FT4及TSH)、血清Hcy及Lp(a)水平的变化.结果 患者甲状腺功能恢复正常后,血清Hcy及Lp(a)水平较治疗前相比下降,差异有统计学意义(P<0.05).结论 甲状腺素替代治疗可降低亚临床甲减患者血清增高的Hcy及Lp(a)水平.
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