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zuo zuo ke zeng jia xiao bai shu xin ji dui wa ba yin de min gan xing he k~+ han liang
Author(s): 
Pages: 49-50
Year: Issue:  3
Journal: Research of Traditional Chinese Medicine

Keyword:  茯苓哇巴因小白鼠Na~+—K~+ATP酶;
Abstract: 采用灌服茯苓煎剂的方法,观察了小白鼠灌服茯苓煎剂以后,心肌对哇巴因敏感性的改变和心肌K+含量的变化。实验结果显示,灌服茯苓煎剂以后,小白鼠对哇巴因的敏感性增加,对照组哇巴因致死量为16.20±2.32ug/g体重,茯苓组为12.47±2.31ug/g体重(P<0.05)。心肌组织K+含量测定显示茯苓增加正常心肌的K+含量。空白对照组干燥心肌K+含量为5.36±2.11ppm/mg,而茯苓组为6.95±1.98ppm/mg。(P<0.05)。实验结果提示茯苓可能对细胞内K+含量有调控作用。其机制可能是通过增加Na+—K+ATP酶活性而实现。
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