Author(s): Hu Sukun Zhou Xiajing Zeng Xiaolian Dou Zhiliang Li Xiaohe Wu Jiang Pathological Department, Central Laboratory, China Academy of Traditional Chinese Medicine
Pages: 37-42
Year: 1986 Issue:  1
Journal: Journal of Traditional Chinese Medicine
Keyword:  临床应用; 实验研究; 中西医结合; 大黄; 证研究; 老年病; 会议资料; 脾虚证动物模型; 大鼠; 防治;
Abstract: <正> This paper reports the experimental results oftwo batches of 24 male Wistar rats.In each batch,13 rats were controls and 11 were given Radixet Rhizoma Rhei decoction in 200% concentration(1.5 ml twice a day for 4 days for the first batchand 2.5 ml mornings and 2.0 ml afternoons for 10days for the second batch).The controls were giventhe same amount of distilled water.Histologicalexaminations showed that the lymphoid organs ofthe experimental animals including thymus,spleen,mesenteric lymph nodes and Peyer’s patches weremuch smaller than those of the controls,particularlythe thymus.The white pulp of the spleen wasatrophied to various degrees.On the other hand,the adrenal glands of the experimental rats werelarger than those of the control animals.No obviouschanges were seen in other organs.The resultsshowed that Radix et Rhizoma Rhei appeared tohave selective inhibitive effect on the immune organsin Wistar rats.