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Experimental Researches of the Effect of "WK” Contraceptive
Author(s): WANG Zuoyi, WANG Jiuyuan, ZHU Bide, ZENG Zhengguang
Pages: 275-
278
Year: 2001
Issue:
4
Journal: NATIONAL JOURNAL OF ANDROLOGY
Keyword: 中药; 杀精栓; 实验研究;
Abstract: 目的:了解中药"五苦栓”杀精、抑菌作用. 方法:运用中药五倍子、苦参粗提物配制成杀精栓剂(WK),对大鼠精子行杀精、生育、阴道粘膜刺激及体外抑菌试验. 结果: WK具有较明显杀精作用,其体外杀精效果在高浓度组超过NP-9阳性对照组(P<0.01),中等浓度时与NP-9无显著性差异(P>0.05).体内杀精效果与NP-9无差异(P>0.05).对淋病奈瑟菌及霉菌的抑制作用强于NP-9(P<0.01),且安全性实验未发现有明显副作用. 结论:"五苦栓”杀精及体外抑制淋病奈瑟菌、霉菌作用确切,具有临床开发价值.
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