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Determination of transferrin, microalbumin and IgG in urine of children with kidney dieseas and its clinical significance
Author(s): 
Pages: 146-148
Year: Issue:  3
Journal: JIANGXI JOURNAL OF MEDICAL LABORATORY SCIENCES

Keyword:  肾病综合征肾炎转铁蛋白微量白蛋白免疫球蛋白G;
Abstract: 目的探讨肾脏疾病患儿尿转铁蛋白(TRF)、微量白蛋白(MA)和IgG浓度变化及其临床意义.方法速率散射比浊法检测60例肾病综合征(肾病),25例肾小球肾炎(肾炎)及30例健康对照尿TRF、MA及IgG浓度.结果(1)肾病活动期尿TRF、MA及IgG浓度分别高于缓解期和对照组(P<0.01),而肾病缓解期组尿TRF、MA及IgG浓度与对照组间差别无显著意义(P>0.05);(2)肾炎组尿TRF、MA及IgG浓度与对照组间差别有显著意义(P<0.01);(3)肾小球基底膜轻微损害的患者,尿IgG与TRF浓度比值(IgG/TRF)小于0.09,而肾小球基底膜严重损害的患者,IgG/TRF大于0.23.结论肾炎和肾病活动期尿TRF、MA及IgG浓度显著升高;尿IgG与TRF浓度比值作为蛋白尿选择指数(SPI),有临床参考价值.
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