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hui su ling yin qi jia tu zuo shen jing he zuo shen jing jing luan xing fang dian de ji zhi fen xi
Pages: 457-462
Year: Issue:  5
Journal: Acta Physiologica Sinica

Keyword:  dimeflinephrenic nerve dischargeconvulsive dischargebrainstem reticular formationrespiratory centernucleus tractus solitari(?)s;
Abstract: Experiments were carried out on 28 locally anesthetized,vagotomized,immo-bilized with Flaxedil and artificially ventilated rabbits.Dimefline-induced con-vulsive discharges were observed in tibial and phrenic nerves,nucleus tractus soli-tarius(NTS)and brainstem reticular formation.Tonic and clonic convulsive burstoccurred in all of these areas after intravenous injection of dimefline(1 .5mg/kg).There were partial synchronous bursts between units in brainstem reticular forma-tion and peripheral nerves.From the results of transection of brainstem and spi-nal cord we deduce that brainstem reticular formation might be the main originalsites where dimefline-induced convulsions are induced.Tractotomy experimentsindicate that discharge in peripheral nerves may be mediated by reticulospinal tract.
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