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Effects of spinal proliferation of shengxie capsules on immune mediated mice with aplastic anacemia
Author(s): ZHOU Dongzhi, WANG Lingling, ZOU Peng, MA Jing, LI Long
Pages: 118-
120
Year: 2001
Issue:
3
Journal: NORTHWEST PHARMACEUTICAL JOURNAL
Keyword: 再生障碍性贫血; 生血胶囊; 补肾; 健脾; 骨髓;
Abstract: 为了探讨生血胶囊对免疫介导的再生障碍性贫血(再障)小鼠骨髓增殖的影响,建立免疫介导的再障小鼠模型,分别胃饲生血胶囊7g生药/kg及2.3g/kg,2次/ 日,连续9天,并以生血丸1号为对照.于制模第10天处死动物,检测外周血白细胞数及股骨骨髓有核细胞数(BMNC),股骨中段骨髓切片HE染色行病理形态学观察.结果表明:生血胶囊组白细胞数、股骨BMNC及骨髓造血组织容量均显著高于模型对照组(P<0.05-0.01) ,生血胶囊大剂量组与生血丸1号组比较无显著差异(P>0.05).说明生血胶囊能促进再障小鼠骨髓增殖.
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