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mi zou shen jing yi dao su xi tong . ji xie di kuo zhang wei dui yu jia si suo yin qi de yi dao su fan she xing fen mi de ying xiang
Pages: 119-126
Year: Issue:  2
Journal: Acta Physiologica Sinica

Keyword:  胰岛素分泌反射性迷走神经假饲扩张食物橡皮球抑制性正常血糖血糖水平;
Abstract: We have reported in the previous paper(Acta Physiologica Sinica.19,337, 1955)that sham feeding causes reflex secretion of insulin through the vagi in dogs provided with esophageal fistula and with the adrenal medulla inactivated.The change of blood sugar concentration was followed as an indicator of insulin secretion.Since the stomach is distended in case of normal feeding,the present work studied whether the distention of stomach would influence this reflex secretion of insulin after sham feeding.Distention of the stomach was done by a balloon filled either with 250 or 500 cc of air or water at 38℃. The results showed that distention of the stomach invariably caused a decrease of the reflex secretion of insulin due to sham feeding.The more the volume used for distention,the greater was the decrease of the insulin secretion.The effect was also greater when the distention was done with water than with air of the same volume.This latter difference was presumably duc to the additional factor of weight with water.Furthermore,the decrease was greater when the distention was done a few minutes before than at the same time with sham feeding. From the above results,it seems reasonable to suppose that distention of the stomach by food during normal feeding would reduce but not abolish the reflex secretion of insulin induced by the act of taking food. The significance of excitation of vago-insulin system in bringing about an insulin secretion during normal feeding has been discussed.
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