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pi xu huan zhe wei zhan mo dan jian neng shen jing zhong mo de xing tai bian hua yu ji neng yi yi de tan tao
Author(s): 
Pages: 6-9+78
Year: Issue:  6
Journal: China Journal of Traditional Chinese Medicine and Pharmacy

Keyword:  脾虚/病理生理学胃粘膜/病理学腺苷环-磷酸/血液鸟苷-磷酸/血液胆碱能纤维/超微结构;
Abstract: 本文报道应用超微结构体视学定量分析方法观察81例脾虚患者胃粘膜胆碱能运动神经终末的变化,并结合血cAMP、cGMP含量的验定,探讨了形态改变与机能之间的联系。结果表明,脾虚气滞组患者胆碱能神经终末内乙酰胆碱递质小泡显著多于脾胃气虚组(p<0.001),血cGMP含量明显高于脾胃气虚组(p<0.002)和正常对照组(p<0.02);血cAMP/cGMP比值则明显低于其它两组(P<0.005—0.001);此结果从超微结构水平提供了脾虚气滞型患者胃肠胆碱能神经功能偏亢的形态学依据,从而提示胆碱能神经偏亢可能为此型患者发病的一个重要机制。
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