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xin zang zhi shi shou shu huan zhe wei shu qi wei ye ph zhi de bian hua
Author(s): 
Pages: 58-60
Year: Issue:  S1
Journal: Academic Journal of Second Military Medical University

Keyword:  extracorporeal circulationpH monitoringgastric juice;
Abstract: Objective:To investigate the changes and its affecting factors about gastric acid secretion during perioperative period in 24 patients undergoing openheart surgery. Methods:Gastric pH was continuously monitored from the beginning of the operation to 24 h after cardiopulmonary bypass (CPB). Results:Gastric pH began to increase from the induction of anesthesia ,and kept above 4.0 during the whole operative(including CPB) period, and the decline of gastric pH after CPB to base line took about 69 h. The changes of gashric pH was related to aortic acrossclamp time,hypoperfusion and the use of adrenine. Conclusion:Gastric acid secretion is inhibited mainly by hypothermia, ischemia and hypoxia induced by CPB, heart operation and drugs. Gastric pH monitoring has an important clinic significance in reflecting the gastrointestinal secretion function after cardiac surgery.
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