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man xing yi xing gan yan huan zhe raas de bian hua ji lin chuang yi yi
Author(s): 
Pages: 47-49
Year: Issue:  1
Journal: Acta Universitatis Medicinalis Nanjing

Keyword:  血管紧张素Ⅱ醛固酮肝硬化;
Abstract: 报告33例慢性乙肝患者血浆血管紧张素Ⅱ(AT-Ⅱ)和醛固酮测定的结果。慢性迁延性肝炎和慢性活动性肝炎稳定期血浆(AT-Ⅱ)与正常对照没有差别,醛固酮比正常值增加2倍以上,无腹水的肝硬化病人AT-Ⅱ正常,而醛固酮比正常对照高2倍以上。有腹水的肝硬化病人AT-Ⅱ、醛固酮均较对照增高5倍以上。25例慢性乙肝患者于速尿激发后AT-Ⅱ水平显著增高。以上结果提示腹水形成与有效血容量降低及肾素、AT-Ⅱ和醛固酮系统(RAAS)兴奋有关,故肝硬化失代偿期应用强利尿剂要有限量,以免造成严重后果。
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