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THE EFFECT OF SEX HORMONE IN MILU ANTLER ON THE REPRODUCTIVE SYSTEM OF RAT AND MOUSE
Author(s): 
Pages: 180-181
Year: Issue:  2
Journal: ACTA ANATOMICA SINICA

Keyword:  性激素麋鹿茸生殖系统大鼠小鼠;
Abstract: Objective To study the influence of the sex hormone in the miluantler through the observing the effect that the sex hormone in the milu an tler have on the reproductive organs of the rat and mouse. MethodsUsing the mixed solvent of ethanol-acetone to extract th e sex hormone from milu antler, and using the rotatory evaporator to get the sex hormone concentrate from the milu antler extractive; using the HPLC to determin e the content of the oestradiol-17 β. By providing rats the milu antler concen trate and standard oestradiol-17 β solution for the mouth respectively, and us ing the morphological method to observe the effect on the reproductive organs. By using the above method and anatomizing and viscerating the uterus and ovary of experimental mouse, calculating the proportion of the weight of the reproduc tive organs. Results Compared with mouse among the normal group, the mouse amon g the tested group has substantial growth on the weight of uterus and ovary.The compensatory growth and change of the uterus and vagina of the emasculation-rat have been appeared after giving sex hormone concentrate from milu antler or sta ndard oestradiol-17 β solution. Conclusion The milu antler concentrate can substantially promote t he growth of the reproductive organs of the female rat and mouse, the milu antle r extractive has the same effect as the oestradiol-17 β.
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