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zuo lv pi zuo dui nao xue shuan bing ren de xue shuan wan b2 de yi zhi
Pages: 176-178+254
Year: Issue:  3
Journal: Acta Academiae Medicinae Suzhou

Keyword:  TiclopidineTXB_2thromosis;
Abstract: 15 patients with acute cerebral thrombosis were treated withTiclopidine at the dosage of250mg/d for three months.The alterations of TXB_2 level in plasma and platelet TXB_2 productioninduced by ADP were observed.Two weeks after administration of the drug,plasma TXB_2 level de-creased significantly and platelet TXB_2 production induced by ADP was remarkly inhibited.These(?)results suggest that the antiplatelet efficiency of Ticlopidine might be,in part,related to the inhibi-tion of arachidonic acid metabolism in platelets.
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