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hap/dom ji hap/dap fang an zhi liao xiao er ji xing fei lin ba xi bao bai xue bing 30 li bao gao
Author(s): 
Pages: 188-190+256
Year: Issue:  3
Journal: Acta Academiae Medicinae Suzhou

Keyword:  acute nonlymphocytic leukemiacomplete remission rate;
Abstract: In order to test the efficacy of HAP/DOM and HAP/DAP chemotherapy regimen on indu-cing remission of acute nonlymphocytic leukemia(ANLL),we randomly assigned 30 children withANLL to recive either HAP/DOM regimen(group I,12 cases)or HAP/DAP regimen(groupⅡ,18 cases).We found that the complete remission(CR) rate was 75% in group Ⅰ and 72.2%in group Ⅱ.CR was achieved by about 2.5 and 3.2 regimen myelosuppression was observed ei-ther in the later half stage of the first regimen or in the second.The white blood cell count de-creased later on.Patients with bone marrow depression seemed to have a higher CR rate.BY ourclinical experience,relipse remains to be a challenge.The problems concerning with optimaltherapeutic regimen,intensive chemotherapy after remission and the continual therapy to achieveprolonged remission duration still remain controversial.
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