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nkcf jian ce zai ji bing zhen duan zhong de ying yong
Author(s): 
Pages: 185-187+255
Year: Issue:  3
Journal: Acta Academiae Medicinae Suzhou

Keyword:  NK celltumorMTT colormetric method;
Abstract: NKCF is a lymphokine released by NK cells to kill the sensitive targets.In this paper,the ac-tivity of NKCF patients with malignant tumor,SLE and asthma was observed by 3~H-TdR incor-porated into the DNA and the stimulating index(SI) of their lymphocytes.The results showthat.(1)the activity of NKCF in patients with three different types of malignant tumors wasmarkedly reduced,but their cpm and SI were nearly at the normal level;(2)the level of NKCF inpatients with SLE decreased obviously and the SI increased slightly;(3)the activity of NKCF inpatients with asthma did not change but the cpm and SI increased markedly.Our results suggestthat the NKCF assay in the clinical practice is conductive to the diagnosis of diseases such as malignant tumors and SLE,but the detection of cellular immunity is more significant for the asthmapatients.
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