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nao chui ti yu zhi fang de zhuan yun
Pages: 105-109
Year: Issue:  2
Journal: Acta Physiologica Sinica

Keyword:  脂肪含量注射四氯化碳四氧化碳垂体前叶生长激素转运截除玉米油脑垂体;
Abstract: It is well known that the anterior pituitary gland is related to fat mobilization. The present study is to find out if fat mobilization is still possible in the absence of the pituitary gland. Female albino rats of 180—220 g in weight were divided into four groups.The rats in group one were hypophysectomized.Three days after the operation 0.5 ml of carbon tetrachloride dissolved in 0.5 ml of corn oil was injected subcutaneously into each rat.The injection was repeated 8 hours later.Twenty-four hours after the first injection the animals were sacrificed and the total liver lipids were determined.The rats in group two were treated similarly except that the carbon tetrachloride was omitted from the injection.The rats in group three and group four were sham-operated and then treated in the same way as those in group one and group two respectively.All rats were fasted after the first injection. In the hypophysectomized animals carbon tetrachloride treatment caused an average increase in liver lipids of 59 per cent calculated in terms of body weight.In the intact animals(sham- operated)the increase in liver lipids as a result of carbon tetrachloride treatment was 122 per cent. The result shows that while fat mobilization into the liver is still possible in the absence of the pituitary gland,it perhaps is carried on tess actively in the hypophysectomized animals in comparison with the intact animals.
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