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Experimental Study of Preventing Ovariectomized Rats from Osteoporosis by Vaccaria segetalis
Author(s): 
Pages: 58-59
Year: Issue:  5
Journal: Journal of Sichuan of Traditional Chinese Medicine

Keyword:  王不留行 骨质疏松症 实验研究;
Abstract: 目的:探讨王不留行防治去势大鼠骨质疏松症的作用。方法:运用切除大鼠卵巢的方法建立大鼠去势骨质疏松模型,分假手术组、模型组(去除卵巢组)、E2组(去除卵巢+尼尔雌醇)、药物组(去除卵巢+王不留行)。术后3个月,测血清IL-1、IL-6、TNF-α含量。结果:王不留行可明显降低血清IL-1、IL-6、TNF-α含量(P<0.01)。结论:王不留行对去势大鼠骨质疏松症有明显的防治作用,这种作用可能与王不留行的雌激素活性,降低骨的转移率和增加骨形成有关。
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