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Experimental research of screening of peptides binding to silk fibroin fiber by phage display technology
Author(s): 
Pages: 17-20
Year: Issue:  1
Journal: Journal of Southwest University for Nationalities(Natrual Science Edition)

Keyword:  噬菌体展示肽库技术短肽蚕丝蛋白肽库蚕丝;
Abstract: 采用噬菌体随机肽库展示技术研究与蚕丝纤维蛋白连结的功能性短肽的淘选方法.实验结果显示,淘选的与蚕丝纤维蛋白连结的功能性短肽都包含有一个相同的氨基酸残基序列QSWS.噬菌体与蚕丝蛋白的连结试验和合成肽与蚕丝蛋白的连结试验都证实了QSWS序列与蚕丝蛋白连结的重要性.随着对淘选方法进一步改进和优化,这些功能性短肽将有助于对蚕丝进行功能化改造,可拓宽蚕丝在生物材料领域中的应用.
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