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Management of thyroglossal duct carcinoma: report of five cases
Author(s): 
Pages: 1013-1016
Year: Issue:  12
Journal: Chinese Journal of Otorhinolaryngology Head and Neck Surgery

Keyword:  Thyroglossal CystThyroid neoplasmsDiagnosisTherapy;
Abstract: 目的 探讨甲状舌管癌的临床特点、诊断、手术范围及预后.方法 回顾性分析1991-2011年收治的110例甲状舌管疾病患者的临床资料,其中5例经术后病理确诊为甲状舌管癌,乳头状癌4例,鳞状细胞癌1例.5例患者均为男性;年龄17~73岁,中位年龄41岁.1例乳头状癌患者术前即合并肺转移.5例患者均行手术治疗,其中2例接受Sistrunk术(切除肿瘤、甲状舌管及部分舌骨),1例行Sistrunk术+甲状腺结节切除术,1例合并肺转移的患者行Sistrunk术+甲状腺全切除术+中央区淋巴清扫术,1例鳞癌患者行Sistrunk术+受侵组织扩大切除术.结果 术后2例乳头状癌患者行促甲状腺激素抑制治疗,其中1例合并肺转移患者行核素治疗,其余3例患者均未行进一步治疗.术后随访14 ~45个月,1例73岁甲状舌管鳞癌患者术后2个月复发,并于术后7个月死于肿瘤复发,其余患者均生存.结论 甲状舌管癌临床少见,确诊依赖术后病理检查,外科手术为主要治疗手段.对于低危患者,Sistrunk术式可能是一种合适的治疗方法.
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