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A 48-week antiviral efficacy of combination therapy of Shuanghu Qinggan Keli and entecavir tablets on HBeAg-positive patients with chronic hepatitis B
Author(s): 
Pages: 232-234
Year: Issue:  4
Journal: INFECTIOUS DISEASE INFORMATION

Keyword:  乙型肝炎慢性乙型肝炎e抗原抗病毒药中西医结合;
Abstract: 目的 观察双虎清肝颗粒联合恩替卡韦片治疗HBeAg 阳性慢性乙型肝炎(chronic hepatitis B,CHB)的临床疗效.方法 将120 例HBeAg 阳性CHB 患者随机分为治疗组和对照组,每组60 例.治疗组给予双虎清肝颗粒联合恩替卡韦片治疗,对照组给予恩替卡韦片治疗,治疗48 周后比较2 组ALT 复常率、HBeAg 转阴/血清学转换率、HBV DNA 水平的变化及主要症状体征的改善情况.结果 治疗组ALT 复常率、HBeAg 转阴/血清学转换率及主要症状体征改善情况均显著优于对照组.结论 双虎清肝颗粒联合恩替卡韦片治疗HBeAg 阳性CHB 患者,在恢复肝功能、加快HBeAg 转阴/血清学转换及改善患者临床症状等方面有较满意的疗效.
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