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Compatible stability of Reduning Injection with acyclovir
Author(s): 
Pages: 393-395
Year: Issue:  4
Journal: Drugs & Clinic

Keyword:  热毒宁注射剂阿昔洛韦配伍稳定性吸光度吸收光谱pH值;
Abstract: 目的 探索热毒宁注射液与阿昔洛韦配伍的稳定性.方法 在室温25℃观察两种药物混合液在60min内的外观、pH值、光谱图变化.结果 两种药物较高浓度混合液会立即出现浑浊和颜色改变,较低浓度混合液的外观清澈透明、微黄;低浓度混合液60min内的pH值稳定;各时间点的吸光度值显著下降,质量分数明显减少.结论 热毒宁注射液与阿昔洛韦无论浓度高低均存在配伍禁忌,建议避免混合应用.
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