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Distribution and resistance surveillance of 104 clinical strains of Serratia marcescens in Anhui Province
Author(s): 
Pages: 524-528
Year: Issue:  9
Journal: Chinese Journal of Infectious Diseases

Keyword:  SerratiaMicrobial sensitivity testsDrug resistancebacterial;
Abstract: 目的 探讨黏质沙雷菌感染的临床分布及耐药特点,为临床诊断和治疗提供依据.方法 104株黏质沙雷菌药物敏感试验采用琼脂稀释法,结果依据临床实验室标准化委员会2010年推荐的标准.率的比较采用x2检验.结果 黏质沙雷菌在呼吸道痰标本中检出率最高(62株,59.6%),主要分布于呼吸内科(35株,33.7%)、ICU(24株,23.1%)、老年病科(17株,16.3%).黏质沙雷菌对氨苄西林、庆大霉素、头孢唑啉的耐药率较高,分别为90.4%、86.5%、79.8%;对第三代头孢菌素的耐药率为24.0%~43.3%,未发现对亚胺培南、美罗培南耐药菌株.与头孢西丁耐药菌株比较,头孢西丁非耐药菌株对哌拉西林(82.9%比28.6%)、头孢他啶(63.4%比9.5%)、氨曲南(68.3%比9.5%)、阿米卡星(68.3%比20.6%)、环丙沙星(48.8%比19.1%)、氯霉素(90.3%比58.7%)等抗菌药物的耐药性明显降低(均P<0.05).结论 黏质沙雷菌是目前医院感染重要的条件致病菌之一,对多种抗菌药物耐药,临床应加强对黏质沙雷菌耐药性的监控以防止耐药菌株的传播流行.
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