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Application of metabonomics in liver and kidney injury research
Author(s): HE Mu, YAO Wei-feng, CAI Xiu-jiang, DING An-wei, JIANG Ye-juan
Pages: 924-
930
Year: 2012
Issue:
8
Journal: Chinese Journal of Clinical Pharmacology and Therapeutics
Keyword: 代谢组学; 肝损伤; 肾损伤; 进展;
Abstract: 代谢组学是近年来新发展起来的一门组学,已成为生物医学研究领域的新热点.由于其广泛的应用前景,目前已是系统生物学的重要组成部分.肝损伤及肾损伤是临床常见的危害人类健康的疾病,但目前的指标缺乏特异性,且灵敏度不高,造成临床上难以对肝肾损伤做出准确而及时的预警和监测.代谢组学能从代谢的角度整体分析疾病,快速、安全地对疾病的严重程度进行判别,在肝肾损伤的早期诊断等方面的研究已初显优势.本文主要综述了代谢组学技术在肝肾损伤研究中的应用现状.
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