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Effects of “Weiqiyin Drink” in Reversing Chronic Atrophic Gastritis Complicated with Precancerous Morbid Cells
Author(s): HU Hongyi, ZHENG Hongbin, LU Xiong, GONG Yuping, MA Guitong
Pages: 32-
34
Year: 2001
Issue:
1
Journal: CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE ON DIGESTION
Keyword: 胃癌前病变; 胃祺饮;
Abstract: Objective:To observe the functions of “Weiqiyin Drink” in reversing chronic atrophic gastritis complicated with precancerous morbid cells.Methods:In animal experiment,precancrous lessions of gastric cancer models were induced by MNNG in Wistar rats. The rats were divided into treating group,protective group and control group,and treated with “Weiqiyin Drink”,folacin and placebo before the isolation of gastric,respectively.Proliferative cell nucleus antigen(PCNA),apoptosis index,change in expression of ras oncogene protein P21 in slices of precancerous morbid tissues of gastric mucosa were measured by immunohistochemistry and inside end labeling(TUNEL) after using the drugs.Results:It showed that in Chinese herbal group PCNA and P21 expressions decreased remarkably,significantly different than in other groups(P<0.01~0.05).In the meantime,“Weiqiyin Drink”,could increase the index of apoptosis.Conclusion:“Weiqiyin Drink” has the effect of strengthening healthy qi to eliminate pathogens and has better reversing function in proliferation of morbid cells before gastric cancer.
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