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Efficacy of dexmedetomidine as an adjunct to combined intravenous-inhalational anesthesia for removal of foreign body in trachea in children
Author(s): 
Pages: 632-634
Year: Issue:  5
Journal: Chinese Journal of Anesthesiology

Keyword:  DexmedetomidineAnesthesiageneralChildTracheaForeign bodies;
Abstract: 目的 评价右美托咪啶辅助静吸复合全麻用于小儿气管异物取出术的效果.方法 拟行气管异物取出术患儿60例,性别不限,年龄1~4岁,体重8 ~ 23 kg,ASA分级Ⅰ或Ⅱ级,采用随机数字表法,将患儿随机分为静吸复合全麻组(Ⅰ组)和右美托咪啶辅助静吸复合全麻组(Ⅱ组),每组30例.入室后面罩吸入8%七氟醚诱导入睡,入睡后减至4%,Ⅱ组静脉输注右美托咪啶0.5 μg/kg,随后静脉注射异丙酚2 mg/kg,接着静脉输注异丙酚6mg·kg-1·h-1和瑞芬太尼0.15 μg·kg-·min-1维持麻醉,Ⅰ组除不用右美托咪啶外余同Ⅱ组,2 min后停止吸入七氟醚开始置入硬支气管镜.于进镜前、进镜1和5 min时记录HR和SpO2,记录呼吸抑制、喉头水肿和心动过缓等的发生情况,术后记录异丙酚和瑞芬太尼总用量、镜检满意情况及苏醒时间.结果 与Ⅰ组比较,Ⅱ组患儿进镜1和5 min时HR降低,进镜1 min时SpO2升高,异丙酚和瑞芬太尼用量减少,手术时间缩短,苏醒时间延长,镜检满意度升高,呼吸抑制和喉头水肿发生率降低(P<0.05).结论 右美托咪啶辅助静吸复合全麻用于小儿气管异物取出术的效果较静吸复合全麻好,且并发症少.
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