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Advance on cell model for oral drug absorption
Author(s): 
Pages: 292-297
Year: Issue:  5
Journal: World Clinical Drugs

Keyword:  口服药物细胞模型Caco-2细胞MDCK细胞M细胞药物溶出/Caco-2细胞;
Abstract: 多种细胞模型如最常用的Cao-2和MDCK细胞,以及新近开发的MDCK-MDR1、M细胞、药物溶出/Caco-2细胞组合、HT-29和TC7细胞等均可用于口服药物吸收的评价,但也存在一定的局限性.本文综述各类细胞模型的特点及其应用等相关研究进展.
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