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Diagnosis and management of critical limb ischemia in diabetic patients
Author(s): 
Pages: 266-269
Year: Issue:  5
Journal: World Clinical Drugs

Abstract: 以动脉粥样硬化为基础的外周动脉疾病(PAD)好发于糖尿病患者.重症肢体缺血(CLI)指的是肢体动脉闭塞致血流不能满足静息时肢体代谢需要的状态,是PAD的严重表现.CLI的治疗包括戒烟、血糖控制、他汀类药物、降压和抗血小板治疗及血运重建,不适合血运重建或血运重建不成功者可使用前列腺素类药物.基因治疗和干细胞治疗的价值尚待进一步研究.本文综述CLI的临床表现以及药物治疗研究进展.
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