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huan lin suan xian zuo pu jia an zhi liao huan man xing xin lv shi chang lin chuang guan cha
Author(s): 
Pages: 925-926
Year: Issue:  8
Journal: Research of Traditional Chinese Medicine

Keyword:  环磷酸腺苷葡甲胺 缓慢性心律失常 心率;
Abstract: 目的观察环磷酸腺苷葡甲胺(心先安,MAC)治疗缓慢性心律失常的临床疗效。方法将46例缓慢性心律失常患者随机分为MAC组和对照组,各23例,对照组给予常规治疗,包括扩血管、利尿、降压、改善心功能等。MAC组在对照组治疗基础上加用MAC 120mg加入葡萄糖液(或生理盐水)250mL静脉输注,每日1次,14d为1个疗程。观察两组治疗前后24h总心率、平均心率、最小心率的变化、心电图和临床症状改善情况。结果 MAC组治疗后24h总心率、平均心率和最小心率明显提高,差异有统计学意义(P<0.05);与对照组治疗后比较,MAC组24h总心率、平均心率和最小心率明显提高,差异有统计学意义(P<0.05)。临床症状疗效总有效率,MAC组为78.3%,对照组为87.0%;心电图疗效总有效率,MAC组为73.9%,对照组为87.0%。MCA组临床症状疗效、心电图疗效总有效率均优于对照组(P<0.05)。结论 MAC能增加缓慢性心律失常患者的心率,可提高临床有效率,改善临床症状,提高生活质量。
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