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Percutaneous absorption of triptolide biological patch in vitro
Pages: 236-238
Year: Issue:  3
Journal: World Phytomedicines

Keyword:  雷公藤内酯醇生物贴雷公藤内酯醇体外透皮吸收高效液相色谱;
Abstract: 目的 研究雷公藤内酯醇生物贴的体外经皮吸收特点.方法 利用改良Franz扩散池研究雷公藤内酯醇生物贴的经皮吸收特点,以HPLC法测定雷公藤内酯醇的经皮吸收量.结果 雷公藤内酯醇生物贴中的雷公藤内酯醇在24 h内以一级动力学经皮渗透,累积渗透量为2.0573μg/cm2.结论 雷公藤内酯醇生物贴中雷公藤内酯醇的体外透皮吸收效果优于文献报道的巴布剂.
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